Curriculum for Specialty Certificate Examination in Gastroenterology

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Tuesday, 25 September 2012

Mallory Bodies


Mallory bodies are cytoplasmic inclusions within hepatocytes that are composed of cytokeratin intermediate filaments and ubiquities, which are small regulatory protiens that are ubiquitously expressed in eukaryotes. They have a characteristic "twisted rope" appearance on light microscope. Although they are common in alcoholic hepatitis, where they have prevalence of 65%, they are also found in a variety of other condtions. Can you name few?

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