The Specialty certificate in Gastroenterology SCE covers the whole of the curriculum of the specialty training in gastroenterology in the UK. Preparation for this exam requires a wide breadth of knowledge around the curriculum . As knowledge is constantly advancing , awareness of current and updated guidelines is important.This blog is an attempt to pool all resources in one site with regular updates.
Dr Elmuhtady Said
Curriculum for Specialty Certificate Examination in Gastroenterology
Which of the following genetic aberrations is not implicated in the pathogenesis of pancreatic carcinoma?
1-Mutation of the p16 tumor suppressor gene 2-Mutation of the TP53 tumor suppressor gene 3-Mutation of the K-ras proto-oncogene 4-Mutation of the Rb tumor suppressor gene 5-Loss of function of the SMAD4 tumor suppressor gene
Numerous molecular abnormalities have been identified in patients with pancreatic cancer. The most commonly detected mutation is the K-ras proto-oncogene. Mutations are detected in more than 90% of pancreatic ductal adenocarcinomas. Other genetic sites known to contribute to carcinogenesis include p16 SMAD4 and TP53 tumor suppressor genes. The Rb tumor suppressor gene is implicated in retinoblastoma.
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the liver already present. I started on antiviral medications which reduced the viral load initially. After a couple of years the virus became resistant. I started on HEPATITIS B Herbal treatment from ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their treatment totally reversed the virus. I did another blood test after the 6 months long treatment and tested negative to the virus. Amazing treatment! This treatment is a breakthrough for all HBV carriers.
Which of the following genetic aberrations is not implicated in the pathogenesis of pancreatic carcinoma?
ReplyDelete1-Mutation of the p16 tumor suppressor gene
2-Mutation of the TP53 tumor suppressor gene
3-Mutation of the K-ras proto-oncogene
4-Mutation of the Rb tumor suppressor gene
5-Loss of function of the SMAD4 tumor suppressor gene
Numerous molecular abnormalities have been identified in patients with pancreatic cancer. The most commonly detected mutation is the K-ras proto-oncogene. Mutations are detected in more than 90% of pancreatic ductal adenocarcinomas. Other genetic sites known to contribute to carcinogenesis include p16 SMAD4 and TP53 tumor suppressor genes. The Rb tumor suppressor gene is implicated in retinoblastoma.
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
ReplyDeleteliver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.