What is the histologic feature that best discriminates between acute self-limited colitis (e.g., from infection) and chronic idiopathic IBD (see figure above)?
1-crypt archticture distortion ( branching, bifid, shortened glands)
2-odema of lamina properia
3-acute inflammatry cell infitrate
4-crypt abscesses
Many of the histopathologic changes seen in UC are nonspecific and can occur in other colitides, including infection and ischemia. These more acute features include edema of the lamina propria and congestion of the capillaries and venules, followed by an acute inflammatory cell infiltrate. Neutrophilic infiltration of colonic crypts causes cryptitis and crypt abscesses. Histologic findings that characterize a chronic colitis such as UC include crypt architectural distortion, crypt atropy, increased intercryptal spacing, Paneth cell metaplasia, basal lymphoid aggregates, an irregular mucosal surface, and a chronic inflammatory infiltrate.
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
ReplyDeleteliver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.