A life threatening condition of fluid and electrolyte shift causing cardiac failure , pul edema and dysrhythmias.
It occurs in response to feeding after a period of relative starvation and result in low K, Mg and high Ca.
In starvation, intracelluar minerals become depleted, although serum conc may remain normal. When feeding occurs, the relative glycaemia causes increase insulin production. The insulin stimulates protein, fat and glycogen synthesis which requires electrolytes and cofactors such as thiamine. The shift of these electrolytes, especially phosphate result in the syndrome.
Risk of malnutrition should be assessed in all patients admitted to the hospital.
It occurs in response to feeding after a period of relative starvation and result in low K, Mg and high Ca.
In starvation, intracelluar minerals become depleted, although serum conc may remain normal. When feeding occurs, the relative glycaemia causes increase insulin production. The insulin stimulates protein, fat and glycogen synthesis which requires electrolytes and cofactors such as thiamine. The shift of these electrolytes, especially phosphate result in the syndrome.
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