Curriculum for Specialty Certificate Examination in Gastroenterology

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Sunday 6 April 2014

Small Bowel Bacterial overgrowth SBBO

Increased bacterial colonization of the small bowel proximal to the distal ileum .
Presentation: Wt loss, abd pain, diarrhea and mal nutrition.
Late presentation include neurlogical symptoms due to vit B12 and fat soluable vitamins malabsorption.

Causes:
1- Reduce host defence:
Hypogammaglobulinaemia
HIV
Old age
Chronic pancreatitis

2-Excessive bacterial entery to the small bowel:
Atrophic gastritis/ gastric acid suppression
Gastro-jujunostomy
Gastrectomy
Entral fistula

3-Delayed small bowel clearance:
Small bowel/ jujunal diverticula
Scleroderma
Strictures (CD, post surgical)
Pseudo-obstruction
Amyloidosis
Autonomic neuropathy (DM)

Diagnosis:
1-Culture of duodenal aspirate - bacteria level > 10 5 colonoies/ ml 
2-Hydrogen breath test ( non-invasive)


1 comment:

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