Curriculum for Specialty Certificate Examination in Gastroenterology

Countdown to the Examination

Wednesday 21 April 2010

Autoimmune Hepatitis

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1 comment:

  1. A 39-year-old woman has had elevated serum aminotransferase levels for more than a year. Her medical history is notable for type 2 diabetes mellitus and hypertriglyceridemia. Serum test results for possible liver pathogens are negative. Ultrasonography reveals increased hepatic echogenicity. What is the most likely finding on histologic evaluation of a biopsy specimen?

    1-Interface hepatitis with lymphocytoplasmic infiltrate
    2-Nonsuppurative destructive cholangitis
    3-PAS-positive diastase-resistant periportal globules
    4-Perisinusoidal fibrosis and Mallory hyaline bodies
    5-Portal lymphoid aggregates with germinal centers

    1-lists typical findings in cases of AIH,
    2- lists findings in cases of PBC,
    3- lists findings in cases of α1-AT deficiency
    5- lists typical findings in cases of chronic HCV infection.

    Given her demographic profile, this patient is most likely to have NAFLD.
    4 lists typical findings in cases of NAFLD.

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