It has been stained with period-acid Schiff, which strongly stains intrahepatic globules pink [long black arrow]. The hepatocytes containing the globules are concentrated adjacent to a band of fibrous tissue [long black and white arrow]. A mild inflammatory infiltrate and myofibroblastic cells are seen associated with the fibrous tissue [short black and white arrow]. It is likely that this patient has early fibrosis wild mild active hepatitis. If this continues the patient is at risk of developing overt cirrhosis.
Α-1 antitrypsin deficiency results in the accumulation of AAT globules in hepatocytes, which have a pink colour with the diastase-Periodic acid Schiff stain and can be highlighted with the aid of a specific immunohistochemical marker
ReplyDeleteI was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
ReplyDeleteliver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.