Curriculum for Specialty Certificate Examination in Gastroenterology

Countdown to the Examination

Sunday, 21 April 2013

question


Which of the following cell types is correctly matched with the substance they synthesize?
1-Gastric chief cells - Intrinsic factor
2-Islet A cells - somatostatin
3-Islet B cells - amylin
4-Islet D cells - pancreatic polypeptide
5-Islet F cells - glucagon

Islet beta cells produce insulin and amylin, as well as C-peptide, pro-insulin and GABA. Islet D cells produce somatostatin, F cells produce pancreatic polypeptide and A cells produce glucagon. Gastric chief cells produce pepsinogen whilst gastric parietal cells produce acid and intrinsic factor.

3 comments:

  1. Which of the following is the main mediator of meal-stimulated enzyme secretion from the pancreas?

    1-Secretin
    2-VIP
    3-CCK
    4-Glucagon
    5-Acetylcholine

    CCK is the major humoral mediator of meal-stimulated pancreatic enzyme secretion. The circulating concentration of CCK increases with a meal. Experiments using highly specific CCK receptor antagonists have demonstrated that pancreatic enzyme secretion with a meal is largely mediated by CCK. CCK is released from the upper small intestinal mucosa by digestion products of fat and protein and, to a small extent, by starch digestion products. Experimental data suggest that CCK activates afferent neurons in the duodenal mucosa. These afferent neurons mediate an enteropancreatic reflex that causes pancreatic enzyme secretion.

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  2. A 39-year-old man presents with the problem of offensive smelling stools. He has difficulty flushing her stools from the toilet. Which of the following is the most sensitive test for exocrine pancreatic function:-

    A- Amylase

    B-Secretin

    C-Lipase

    D-Cholecystokinin

    E-Gastrin

    Currently, pancreatic secretin stimulation test is the only test of pancreatic function, which has practical clinical utility. It is also considered to be the most sensitive test for detecting exocrine pancreatic insufficiency as a surrogate marker for (early) chronic pancreatitis.

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  3. I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
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    reduced the viral load initially. After a couple of years the virus
    became resistant. I started on HEPATITIS B Herbal treatment from
    ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
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